Atletico Madrid have a chance to pile more King's Cup misery on neighbours Real after eliminating Athletic Bilbao on Wednesday to set up a last-four clash against the bitter city rivals they beat in last year's final.
Barcelona have emerged as favourites to be crowned champions after one defeat in their last 22 Liga games.
Lionel Messi will have another chance to match or surpass Telmo Zarra's six-decade-old La Liga scoring record of 251 goals when Barcelona host promoted Eibar on Saturday.
Atletico Madrid striker Antoine Griezmann struck twice as the Spanish side outclassed hapless Olympique de Marseille 3-0 on Wednesday to win the Europa League for the third time.
News of all that's transpired on and off the football field
A late goal by Toni Kroos sealed victory as Real Madrid defeated an impressive Celta Vigo side 2-1 to win their first home La Liga game of the campaign on Saturday.
The 25-year-old striker, who stands 1.76 metres tall, caught the eye on the big stage against Germany, driving home a penalty at the end of the first half before poking in the ball on 72 minutes following a rare blunder by Germany goalkeeper Manuel Neuer.
Champions Barcelona moved five points clear at the top of La Liga with a 2-1 win at Getafe, while Real Madrid fell to a 2-0 defeat by Real Sociedad.
'This crisis is going to be much bigger than anything we've experienced and anything we do will not be enough but my aim is to help, it might not be enough in some cases but I have to try'
Lionel Messi was back in scoring business for Barcelona on Sunday, leading them to a resounding 4-0 win at home against Villarreal in a near-perfect La Liga opener for the Catalans under new coach Ronald Koeman.
Lionel Messi has been included in Barcelona's squad for Wednesday's Spanish Super Cup second leg at home to Atletico Madrid after recovering from a thigh problem sustained in last week's 1-1 first-leg draw at the Calderon.
Atletico Madrid maintained a two-point lead in La Liga with a 3-0 victory at Las Palmas and Barcelona and Real Madrid stayed hard on their heels with thumping wins over Athletic Bilbao and Sporting Gijon on Sunday.
A round-up of Saturday's football action in La Liga, Bundesliga and Ligue 1.
Hellas Verona produced a huge upset by coming from behind to beat Serie A leaders Juventus 2-1 on Saturday, inflicting a third defeat of the season on the Italian champions. Cristiano Ronaldo set a new Juventus record by scoring in a 10th consecutive league game to put the visitors in front at the Stadio Marc'Antonio Bentegodi after 65 minutes.
A round-up of Sunday's matches in La Liga, Serie A and Bundesliga.
Paris St Germain had a chance to extend their Ligue 1 lead to five points after RC Lens drew 1-1 at Troyes and Olympique de Marseille and Monaco shared the spoils on Saturday.
Barcelona's Luis Suarez netted twice for a 2-1 win over 10-man Atletico Madrid in their Champions League quarter-final, first leg on Tuesday after the visitors' Fernando Torres opened the scoring and was later sent off.
Paris St Germain will play Borussia Dortmund and Barcelona were pitted against an unpredictable Napoli, while Chelsea were drawn against Bayern Munich. City, who will be at home in the second leg, have yet to beat the Spanish side with two draws and two defeats in their previous four meetings.
Messi stretched Barca's lead by finishing off a brilliant move with Luis Suarez in the 50th minute and the Uruguayan joined his close friend and strike partner on 15 league goals by robbing an Eibar defender and finishing inside the near post in the 68th.
David Beckham, one of the so-called "Class of 92", went on to win six Premier League titles under Alex Ferguson at United alongside youth-team buddies Ryan Giggs, Paul Scholes, Nicky Butt, and Gary and Phil Neville. Beckham also won two FA Cups and, memorably, the Champions League in 1999. He topped up his trophy collection with a La Liga winners' medal for Real Madrid and added two MLS Cups during a north American adventure with LA Galaxy.
Atletico Madrid tore apart city rivals Real Madrid 4-0 at home to open up the La Liga title race on Saturday in a triumph crowned by a spectacular overhead kick goal by Saul Niguez.
Lionel Messi marked his 300th La Liga appearance with a record-equalling hat-trick and an assist for Neymar as Barcelona stayed hard on the heels of leaders Real Madrid with a 5-0 romp at home to Levante on Sunday.
River Plate battled back to beat arch Argentine rivals Boca Juniors 3-1 in extra-time in an unforgettable and unique Copa Libertadores final second leg, played in Madrid after violence had seen the original game postponed.
Paris St Germain extended their Ligue 1 lead to 13 points with a 4-3 home victory against Girondins de Bordeaux on Sunday but the French champions were again exposed at the back and had Neymar sent off. A Marquinhos double, Edinson Cavani's 200th PSG goal and a goal by Kylian Mbappe put the capital side on 65 points from 26 games but they lost captain Thiago Silva to a muscle injury and Neymar picked up a straight red card for a late challenge in stoppage time.
News of all that's transpired on and off the football field
A round-up of Wednesday's action in the UEFA Champions League.
Manchester City boss Pep Guardiola has warned his side to beware of Monaco's "killers in the box" when they host the principality club in the first leg of their Champions League, last 16 tie on Tuesday.
Barcelona and Atletico Madrid led a Spanish Armada into the Champions League last 16 with home wins on Wednesday and in-form Aaron Ramsey steadied Arsenal's boat with a battling win against rocky Borussia Dortmund.
Luis Suarez was incredulous after being sent off in Barcelona's thrilling King's Cup semi-final second leg with Atletico Madrid on Tuesday, ruling him out of the final in May after playing a pivotal role in getting his team there.
Paris St Germain's Zlatan Ibrahimovic scored his first Ligue 1 goal this season before missing a penalty as they beat En Avant Guingamp 3-0 to extend their lead to four points on Tuesday.
Argentina will return to Olympic football next year after sealing victory in the South American under-20 qualifying tournament in Uruguay on Saturday.
The result also means second-placed Real Sociedad can reclaim top spot if they beat Eibar on Sunday.
News of all that's transpired on and off the football field.
News of all that's transpired on and off the football field
Atletico Madrid secured a berth in the Champions League group stage for next season and Deportivo La Coruna narrowly escaped relegation when they came from two goals down to draw 2-2 at champions Barcelona on the final day in La Liga on Saturday.
Neymar scored the opener to continue his rich vein of form as 10-man Barcelona won a one-sided La Liga derby against Espanyol.
Former Real youth player Joselu pulled a goal back for Alaves in the 59th minute, powering in a header from a free kick, but Benzema rounded off the victory for second-placed Real with an exquisite solo run and goal in the 70th minute.
Images from the Champions League round of 16 second leg matches played on Tuesday
Atletico Madrid and Royal Challengers again failed when it mattered most.
Genoa blew away Serie A leaders Juventus on Sunday, scoring three times in an astonishing first half hour on the way to a pulsating 3-1 win.